FORMULATION AND EVALUATION OF ORAL HERBAL MEDICATED JELLY FROM GLYCYRRHIZA GLABRA AND PSIDIUM GUAJAVA LINN EXTRACT FOR TREATMENT OF MOUTH ULCER
DOI:
https://doi.org/10.53555/ans.v10i1.2465Keywords:
Mouth ulcer, gelling agent, oral route, oral medicated jelly, Psidium Guajava, Glycyrrhiza glabra, liquorice, H+ K+ -ATPase Inhibition, Acid Neutralizing CapacityAbstract
Mouth ulcers are small sores that form on your gums, lips, tongue, inner cheeks or roof of
your mouth. Lots of different things can cause them, including minor injuries, hormonal changes,
biting your cheeks or tongue, lack of sleep, eating acidic food, emotional stress and oral hygiene.
Psidium Guajava rich in Guaijaverin can be effective for mouth ulcers in terms of reduction of
symptoms of pain and faster reduction of ulcer size further formulating Jelly which has
efficiency to inhibit the growth of the microorganism.. Glycyrrhiza glabra, rich in glycyrrhizin,
exhibits potent antiulcer properties for oral health. Its anti-inflammatory, antimicrobial, and
mucoprotective effects help in healing mouth ulcers, reducing pain, and promoting tissue
regeneration. Additionally, its antioxidant properties aid in preventing ulcer recurrence. Safe and
effective, it serves as a natural alternative for oral ulcer management. The jelly was prepared
using guava leaves and liquorice aqueous extract. Its structure is clear and homogeneous and its
pH value is between 4-7. Recent development of oral medicated jelly is one of the novel
approaches, aims to improve safety and efficacy, it can easily be accept by patient with
Dysphagia, paediatric and geriatric patients. The aim of this review is to addresses briefly about
its advantages, disadvantages, gelling agents, excipients, method for preparation, evaluation
parameters and its Significance over conventional form of drugs. Oral medicated jelly composed
of Glycyrrhiza glabra and Psidium guajava.
Mouth ulcer, gelling agent, oral route, oral medicated jelly , Psidium Guajava, ,
Glycyrrhiza glabra, liquorice, H+ K+ -ATPase Inhibition, Acid Neutralizing Capacity
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